MRKH syndrome is the common name for Mayer-Rokitansky-Küster-Hauser syndrome. MRKH syndrome is a condition where young women are born either without a vagina and uterus or with an underdeveloped vagina and uterus. It is the most common type of vaginal agenesis. Agenesis is Latin for "not developed." Therefore vaginal agenesis means the vagina is not developed.

MRKH affects between one in 4000 and one in 10,000 female births. MRKH syndrome was first described in 1829. However, historical evidence of the condition dates back to 460 B.C.

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