As soon as sugar touches your tongue, your nervous system kicks into high gear. The tongue tells the brain’s “taste center” that you ate something sweet, relaying a message to another part of your brain that eating sweet stuff is good. This is a problematic process for anyone who’s ever tried to shed some pounds, but now, scientists studying mouse brains have found a way to disrupt it. As researchers write in Nature on Wednesday, just because your brain senses sweetness doesn’t mean it has to conflate sweetness with pleasure.

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